Developing Human Connectome Project

The Developing Human Connectome Project aims to map the intricate neural wiring of babies from womb to birth in a revolutionary undertaking. Stunning high-resolution images from 40 newborns were just released, providing researchers an initial basis for analysis and feedback. Led by King’s College London, Imperial College London and Oxford University, the project runs for three more years and is expected to produce thousands of images in the coming months. Capturing the early stages of brain development offers tremendous insight into conditions such as autism, cerebral palsy and attention deficit disorders, The Guardian reports.


Image provided by The Developing Human Connectome Project via The Guardian

Startup Spotlight: PicnicHealth

Weeks before entering graduate school, I was asked to verify compliance with Penn’s vaccination policy. The request seemed simple enough: Are my records online somewhere? Do I have to get something in the mail? Can my old school just inform my new school that I am, in fact, well-immunized…? Ultimately, it took one game of phone tag and a trip to my beloved pediatrician’s office to gather everything I needed. 

I’m embarrassed to think that I was frustrated at the time, for this recount is laughably simple compared to what many endure on a daily basis. A troubling barrier exists between patients and their medical records; for patients of chronic and severe medical conditions, this barrier becomes truly and incredibly daunting. Appointments, tests, diagnoses, prognoses, prescriptions etc. rack up quickly, and when patients are seen at multiple practices simultaneously—which is all too often the case—things are repeated. Information is lost. Details are missed.

Enter PicnicHealth: Co-founder and CEO Noga Leviner knows that managing medical records can be a full-time job, so she made it hers—for Jed, for Hollye, and for many others who find solace in PicnicHealth’s unique offerings. At $33 a month plus a one-time fee of $299, the subscription service meticulously retrieves, organizes, and maintains medical records for you to have seamlessly at your disposal. PicnicHealth does all of the legwork, relieving patients and loved ones of this hellish burden. 

A service of this kind was impossible not so long ago due to legal and technological limitations. The New England Journal of Medicine explores this phenomenon in a 2014 perspective article:

Forty years ago, Shenkin and Warner argued that giving patients their medical records “would lead to more appropriate utilization of physicians and a greater ability of patients to participate in their own care.” At that time, patients in most states could obtain their records only through litigation, but the rules gradually changed, and in 1996 the Health Insurance Portability and Accountability Act entitled virtually all patients to obtain their records on request. Today, we’re on the verge of eliminating such requests by simply providing patients online access. Thanks in part to federal financial incentives, electronic medical records are becoming the rule, accompanied increasingly by password-protected portals that offer patients laboratory, radiology, and pathology results and secure communication with their clinicians by e-mail.

This is a matter of transparency in healthcare, remarkably, the right to access all medical information pertaining to oneself. Having access is essentially useless without proper content management. 

PicnicHealth is thus a battlesuit for chronic patients, protecting them from pitfalls in modern-day documentation and positioning them to receive the best possible medical care. With the potential to offer tremendous foresight in unforeseen circumstances, perhaps aggregation services will become the norm in healthcare. Such empowerment is propitious, without a doubt.

 

In Vitro Brain Breakthrough

“This study is one of the first attempts to combine organoids with bioengineering. Our new method takes advantage of and combines the unique strengths of each approach, namely the intrinsic self-organization of organoids and the reproducibility afforded by bioengineering. We make use of small microfilaments to guide the shape of the organoids without driving tissue identity.” Madeline Lancaster of the MRC Laboratory of Molecular Biology describes to Lab Manager. Organoid refers to lab-grown miniature organ or organ-like tissue, encompassing complex properties such as 3D multicellular composition and self-organization. For the full story, click here.


Image provided by Institute of Molecular Biotechnology of the Austrian Academy of Sciences via Lab Manager